Increased Small Dense LDL and Decreased Paraoxonase Enzyme Activity Reveals Formation of an Atherogenic Risk in Streptozotocin-Induced Diabetic Guinea Pigs

Table 1

Mean blood glucose and lipid profile in type 1 diabetic and control guinea pigs.

Parameter	Control (𝑛=15)	Diabetes (𝑛=5)	𝑃 value
Glucose
(mg/dL)	139.20 ± 9.49	213.40 ± 13.18*	<0.001
TG
(mg/dL)	76.13 ± 28.56	39.80 ± 22.03	0.060
(mmol/L)	0.86 ± 0.32	0.45 ± 0.24
Total cholesterol
(mg/dL)	53.27 ± 10.41	31.20 ± 5.26*	0.023
(mmol/L)	1.38 ± 0.27	0.81 ± 0.14*
LDL
(mg/dL)	34.31 ± 14.87	13.53 ± 2.01*	0.007
(mmol/L)	0.89 ± 0.38	0.35 ± 0.05*
VLDL
(mg/dL)	12.00 ± 1.98	10.47 ± 1.83	0.145
(mmol/L)	0.31 ± 0.05	0.27 ± 0.05
HDL
(mg/dL)	3.00 ± 1.56	7.6 ± 2.79*	<0.001
(mmol/L)	0.08 ± 0.04	0.20 ± 0.07*

Values are mean ± SD.