The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications

Table 1

QTLs involved in glucose intolerance in SDT rats.

QTL	Chr.	Position^a	Trait^b	Inheritance mode	Cross
Gisdt1	1	D1Mit3	Postprandial	Recessive	(BN × SDT) × SDT
Gisdt2	2	D2Got147	Postprandial	Recessive	(BN × SDT) × SDT
Gisdt3	X	DXWox20	Postprandial	X-linked	(BN × SDT) × SDT
Dmsdt1	3	D3Mit12	Postprandial	Dominant, additive	(F344 × SDT) F2
Dmsdt2	8	D8Rat46	Fasting, Postprandial	Recessive	(F344 × SDT) F2
Dmsdt3	13	D13Arb5	Fasting	Recessive	(F344 × SDT) F2
Dmsdt4	14	D14Arb18	Postprandial	Additive	(F344 × SDT) F2

^aThe SSLP markers which are the closest to maximum peaks of QTLs are shown.
^bPostprandial: postprandial blood glucose levels, fasting: fasting blood glucose levels.
Seven highly significant QTLs (Gisdt1, Gisdt2, Gisdt3, Dmsdt1, Dmsdt2, Dmsdt3, and Dmsdt4) for glucose intolerance have been identified in SDT rats. The table is summarized from [25–27].