Clinical Study

Relation of Asymmetric Dimethylarginine Levels to Macrovascular Disease and Inflammation Markers in Type 2 Diabetic Patients

Table 1

Comparison of the common parameters in MVD, non-MVD, and the control group.

MVD (a)non-MVD (b)Control (c)

Age (years)61.86 ± 7.9656.8 ± 8.9455.06 ± 7.46(a-c) , (a-b)
BMI (kg/m2)29.59 ± 4.7630.44 ± 6.2227.83 ± 2.68
SBP (mm/Hg)126.20 ± 13.07125.40 ± 15.31121.77 ± 9.53
DBP (mm/Hg)80.80 ± 8.1677.90 ± 12.8680.80 ± 8.76
D. of diabetes (Years)12.98 ± 7.249.08 ± 5.75
HbA1c (%)9.41 ± 2.639.88 ± 2.93
CCr (mL/min)84.25 ± 40.5595.27 ± 42.38
Albuminuria (mg/day)305.20 ± 946.28110.70 ± 238.78
C-Peptide (ng/mL)2.21 ± 1.772.17 ± 1.23
PBG (mg/dL)171.56 ± 76.20202.72 ± 99.5286.87 ± 8.65(b-c) , (a-c)
Creatinine (mg/dL)1.01 ± 0.250.85 ± 0.180.82 ± 0.15(a-b) , (a-c)
Triglyceride (mg/dL)188.68 ± 109.11185.44 ± 101.35141.19 ± 78.74(a-c) , (b-c)
HDL (mg/dL)50.80 ± 13.9549.74 ± 10.3154.20 ± 13.18
T. cholesterol (mg/dL)181.26 ± 46.90189.16 ± 43.81203.38 ± 33.94
LDL (mg/dL)113.40 ± 36.89121.50 ± 34.24137.58 ± 32.56(c-a) , (c-b)
Sedimentation (mm/hr)25.38 ± 21.8818.60 ± 15.3512.51 ± 8.31(a-c)
CRP (mg/L)7.71 ± 9.216.57 ± 11.422.36 ± 1.85(a-c)
Fibrinogen (mg/dL)386.66 ± 91.74370.32 ± 68.31344.51 ± 55.69(a-c)
Homocysteine (umol/L)11.78 ± 3.8511.38 ± 3.8610.58 ± 3.59
B12 (pg/mL)537.84 ± 381.73449.14 ± 309.35421.03 ± 274.66
Folic acid (ng/mL)9.27 ± 3.579.51 ± 3.589.93 ± 8.14
Car.Int-R (mm)0.96 ± 0.230.89 ± 0.240.78 ± 0.19(a-c)
Car.Int-L (mm)0.93 ± 0.180.93 ± 0.280.79 ± 0.19(a-c) , (b-c)
ADMA (umol/L)0.52 ± 0.230.39 ± 0.160.32 ± 0.13(a-b) , (a-c)

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; D. of diabetes: duration of diabetes.