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Journal of Diabetes Research
Volume 2014 (2014), Article ID 294032, 7 pages
http://dx.doi.org/10.1155/2014/294032
Clinical Study

Vomiting and Dysphagia Predict Delayed Gastric Emptying in Diabetic and Nondiabetic Subjects

1Department of Gastroenterology, Rabin Medical Center, Beilinson Hospital, 39 Jabotinski Street 49100, Petach Tikva, Israel
2Department of Nuclear Medicine, Rabin Medical Center, Beilinson Hospital, Israel
3Department of Biostatistics, Rabin Medical Center, Beilinson Hospital, Israel
4Epidemiology Unit, Edith Wolfson Medical Center, Holon and the Sackler Faculty of Medicine, Tel Aviv University, Israel

Received 9 March 2014; Accepted 17 April 2014; Published 11 May 2014

Academic Editor: Dimitrios Papazoglou

Copyright © 2014 Doron Boltin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Gastroparesis is a heterogeneous disorder most often idiopathic, diabetic, or postsurgical in nature. The demographic and clinical predictors of gastroparesis in Israeli patients are poorly defined. Methods. During the study period we identified all adult patients who were referred to gastric emptying scintigraphy (GES) for the evaluation of dyspeptic symptoms. Of those, 193 patients who were referred to GES from our institution were retrospectively identified (76 (39%) males, mean age years). Subjects were grouped according to gastric half-emptying times (gastric ). Demographic and clinical data were extracted from electronic medical records or by a phone interview. Key Results. Gastric emptying half-times were normal (gastric 0–99 min) in 101 patients, abnormal (gastric 100–299 min) in 67 patients, and grossly abnormal (gastric  min) in 25 patients. Vomiting and dysphagia, but neither early satiety nor bloating, correlated with delayed gastric emptying. Diabetes was associated with grossly abnormal gastric . Idiopathic gastroparesis was associated with a younger age at GES. No correlation was observed between gastric values and gender, smoking, H. pylori infection, HBA1C, or microvascular complication of diabetes. Conclusions Inferences. Vomiting and dysphagia are predictive of delayed gastric emptying in both diabetic and nondiabetic subjects. Diabetes is associated with more severe gastroparesis.