Table of Contents Author Guidelines Submit a Manuscript
Journal of Diabetes Research
Volume 2014, Article ID 363126, 6 pages
http://dx.doi.org/10.1155/2014/363126
Research Article

Effects of Unilateral Nephrectomy on Renal Function in Male Spontaneously Diabetic Torii Fatty Rats: A Novel Obese Type 2 Diabetic Model

1Japan Tobacco Inc., Central Pharmaceutical Research Institute, Biological/Pharmacological Research Laboratories, 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan
2Japan Tobacco Inc., Central Pharmaceutical Research Institute, Toxicology Research Laboratories, 23 Naganuki, Hadano, Kanagawa 257-0024, Japan

Received 23 June 2014; Accepted 7 July 2014; Published 10 August 2014

Academic Editor: Masami Shinohara

Copyright © 2014 Yoshiaki Katsuda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. L. Hoyert, M. P. Heron, S. L. Murphy, and H. C. Kung, “Deaths: final data for 2003,” National Vital Statistics Reports, vol. 54, no. 13, pp. 1–120, 2006. View at Google Scholar · View at Scopus
  2. E. S. Schaeffner, T. Kurth, G. C. Curhan et al., “Cholesterol and the risk of renal dysfunction in apparently healthy men,” Journal of the American Society of Nephrology, vol. 14, no. 8, pp. 2084–2091, 2003. View at Google Scholar · View at Scopus
  3. R. Agarwal, “Blood pressure components and the risk for end-stage renal disease and death in chronic kidney disease,” Clinical Journal of the American Society of Nephrology, vol. 4, no. 4, pp. 830–837, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. T. M. Islam, C. S. Fox, D. Mann, and P. Muntner, “Age-related associations of hypertension and diabetes mellitus with chronic kidney disease,” BMC Nephrology, vol. 10, no. 1, article 17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Ritz and A. Stefanski, “Diabetic nephropathy in type II diabetes,” The American Journal of Kidney Diseases, vol. 27, no. 2, pp. 167–194, 1996. View at Publisher · View at Google Scholar · View at Scopus
  6. J. E. Hall, J. J. Kuo, A. A. da Silva, R. B. de Paula, J. Liu, and L. Tallam, “Obesity-associated hypertension and kidney disease,” Current Opinion in Nephrology and Hypertension, vol. 12, no. 2, pp. 195–200, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Petersen, J. Ross, and R. Rabkin, “Effect of insulin therapy on established diabetic nephropathy in rats,” Diabetes, vol. 37, no. 10, pp. 1346–1350, 1988. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Matsui, T. Ohta, H. Morinaga et al., “Effects of preventing hyperphagia on glycolipid metabolic abnormalities in Spontaneously Diabetic Torii fatty rats,” Animal Science Journal, vol. 79, no. 5, pp. 605–613, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Matsui, T. Ohta, T. Oda et al., “Diabetes-associated complications in Spontaneously Diabetic Torii fatty rats,” Experimental Animals, vol. 57, no. 2, pp. 111–121, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Morinaga, T. Ohta, K. Matsui et al., “Effect of food restriction on adipose tissue in spontaneously diabetic Torii fatty rats,” Experimental Diabetes Research, vol. 2009, Article ID 715057, 9 pages, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Ishii, T. Ohta, T. Sasase et al., “Pathophysiological analysis of female spontaneously diabetic torii fatty rats,” Experimental Animals, vol. 59, no. 1, pp. 73–84, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. Katsuda, T. Ohta, K. Miyajima et al., “Diabetic complications in obese type 2 diabetic rat models,” Experimental Animals, vol. 63, no. 2, pp. 121–132, 2014. View at Publisher · View at Google Scholar
  13. Y. Ishii, M. Maki, H. Yamamoto, T. Sasase, M. Kakutani, and T. Ohta, “Evaluation of blood pressure in spontaneously diabetic torii-Leprfa rats,” Experimental Animals, vol. 59, no. 4, pp. 525–529, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Ishii, M. Maki, H. Yamamoto, T. Sasase, M. Kakutani, and T. Ohta, “Blood pressure characteristics of female spontaneously diabetic Torii-Leprfa rats,” Journal of Veterinary Medical Science, vol. 73, no. 4, pp. 501–505, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. M. W. Steffes, D. M. Brown, and S. M. Mauer, “Diabetic glomerulopathy following unilateral nephrectomy in the rat,” Diabetes, vol. 27, no. 1, pp. 35–41, 1978. View at Publisher · View at Google Scholar · View at Scopus
  16. M. P. O'Donnell, B. L. Kasiske, F. X. Daniels, and W. F. Keane, “Effects of nephron loss on glomerular hemodynamics and morphology in diabetic rats,” Diabetes, vol. 35, no. 9, pp. 1011–1015, 1986. View at Publisher · View at Google Scholar · View at Scopus
  17. G. S. Lopes, C. C. S. Lemos, C. A. Mandarim-de-Lacerda, and R. Bregman, “Effect of unilateral nephrectomy on renal function of diabetic rats,” Histology and Histopathology, vol. 19, no. 4, pp. 1085–1088, 2004. View at Google Scholar · View at Scopus
  18. B. L. Kasiske, M. P. O'Donnell, M. P. Clearly, W. F. Keane, and F. Phillips, “Effects of reduced renal mass on tissue lipids and renal injury in hyperlipidemic rats,” Kidney International, vol. 35, no. 1, pp. 40–47, 1989. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Oršić, M. Mihalj, M. Moguš et al., “Impaired kidney function in rats six months after unilateral nephrectomy: an old story, a new perspective,” Medicinski Glasnik, vol. 8, no. 2, pp. 185–191, 2011. View at Google Scholar · View at Scopus
  20. T. H. Hostetter, J. L. Troy, and B. M. Brenner, “Glomerular hemodynamics in experimental diabetes mellitus,” Kidney International, vol. 19, no. 3, pp. 410–415, 1981. View at Publisher · View at Google Scholar · View at Scopus
  21. L. Peric Golia and M. Peric Golia, “Aortic and renal lesions in hypercholesterolemic adult, male, virgin Sprague-Dawley rats,” Atherosclerosis, vol. 46, no. 1, pp. 57–65, 1983. View at Publisher · View at Google Scholar · View at Scopus
  22. B. L. Kasiske, M. P. O'Donnell, W. J. Garvis, and W. F. Keane, “Pharmacologic treatment of hyperlipidemia reduces glomerular injury in rat 5/6 nephrectomy model of chronic renal failure,” Circulation Research, vol. 62, no. 2, pp. 367–374, 1988. View at Publisher · View at Google Scholar · View at Scopus
  23. R. F. Gagnon and M. Ansari, “Development and progression of uremic changes in the mouse with surgically induced renal failure,” Nephron, vol. 54, no. 1, pp. 70–76, 1990. View at Publisher · View at Google Scholar · View at Scopus
  24. J. C. Peterson, S. Adler, J. M. Burkart et al., “Blood pressure control, proteinuria, and the progression of renal disease: the modification of diet in renal disease study,” Annals of Internal Medicine, vol. 123, no. 10, pp. 754–762, 1995. View at Publisher · View at Google Scholar · View at Scopus
  25. C. C. Luka, K. Chowa, J. S. Kwok et al., “Urinary biomarkers for the prediction of reversibility in acute-on-chronic renal failure,” Disease Markers, vol. 34, no. 3, pp. 179–185, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. F. L. Nauta, W. E. Boertien, S. J. L. Bakker et al., “Glomerular and tubular damage markers are elevated in patients with diabetes,” Diabetes Care, vol. 34, no. 4, pp. 975–981, 2011. View at Publisher · View at Google Scholar · View at Scopus