The Protective Effects of Insulin and Natural Honey against Hippocampal Cell Death in Streptozotocin-Induced Diabetic Rats

Figure 3

Effects of insulin and honey on apoptosis of neuronal cells in the hippocampus. Apoptosis was evaluated via TUNEL assay with the use of in situ Cell Death Detection Kit at 400x magnification (arrows show the apoptotic cells). A: different parts of hippocampus; C: the control group; D: untreated diabetic group; I: diabetic rats treated with insulin; H: diabetic group treated with honey; I + H: diabetic rats treated with insulin and honey simultaneously.