Vanadyl Sulfate Treatment Stimulates Proliferation and Regeneration of Beta Cells in Pancreatic Islets
Immunohistochemical staining of insulin in pancreatic Langerhans islet beta cells from STZ-diabetic rats. Note that there are more insulin immunopositive cells in the treated STZ-diabetic rats than in nontreated STZ-diabetic rats. Control D (a), D treated with 5 mg/Kg of VOSO4 (b), and D treated with 10 mg/Kg of VOSO4 (c). Ten islets per rat were analyzed. Scale bar: 50 µm.