Decreased Neuronal Bursting and Phase Synchrony in the Hippocampus of Streptozotocin Diabetic Rats
Figure 6
Phase-locking of hippocampal neurons. (a) Epoch of wide-band raw trace as well as corresponding delta oscillation of LFP (band-pass filtered in the frequency band of 1–4 Hz) and spike train. The phase-locking between spike and delta oscillation of LFP is apparent. (b) Phase value rasters (upper panel) and the corresponding phase value (lower panel) distributions of two typical neurons in the control and DM groups. Control rats showed stronger phase-locking phenomenon than diabetic rats. (c) Comparison of phase-locking values between diabetic and control rats. The PLV in control rats was significantly higher than that in diabetic rats () (, Student’s -test). (d) Comparison of delta power ratio between Ctrl and DM groups. There was significant difference between Ctrl () and DM () groups (, Student’s -test). “” represents number of rats and “n” represents number of neurons.
