Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats)

Table 1

Histopathological findings of the eyes in SDT fatty rats at weeks 50 and 60 of age.

Organ; Pathological finding	Sex	Male															Female
	Strain	SD					SDT					SDT fatty					SD					SDT					SDT fatty
	Number of animals	9					6					7					10					11					9
	Grade	−	±	+	2+	3+	−	±	+	2+	3+	−	±	+	2+	3+	−	±	+	2+	3+	−	±	+	2+	3+	−	±	+	2+	3+
Choroid
Infiltration, inflammatory cell		9					6					1	1	3	2		10					11					2	1	5		1
Iris/ciliary body
Infiltration, inflammatory cell		9					4	2				5	2				10					6	5					3	5	1
Deposit, hemosiderin, and trabecular meshwork		9					3	1	2			4	2	1			10					6	5				8	1
Retina
Retinal fold		8	1				3	1	2					4	3		10					9	1	1				1	3	5
Lens
Deformation		9							5	1					7		10					4	2	5			1		2	6
Degeneration, lens fiber (vacuolation/morgani body)		9								6						7	10					3	4	4			1		2	5	1
Hypertrophy/proliferation, epithelium		9					1	2	3			3		3	1		10					11					7		2

−: negative, ±: very slight, +: slight, 2+: moderate, and 3+: severe.