The Association between Serum Uric Acid and Residual β-Cell Function in Type 2 Diabetes

Table 4

Multiple linear regression for β-cell function after grouping by gender.

	INSR30		INSR120		DI30		DI120
	β	S-β	β	S-β	β	S-β	β	S-β
Female
Hypertension (yes = 1, no = 0)	−0.016	−0.012	−0.023	−0.015	—	—	—	—
Years from diagnosis	−0.024	−0.216^#	−0.034	−0.268^#	−0.020	−0.256^#	−0.030	−0.331^#
BMI (kg^2/cm)	0.015	0.082*	0.010	0.050	—	—	—	—
SBP (mmHg)	—	—	—	—	0.001	0.051	0.001	0.008
DBP (mmHg)	—	—	—	—	−0.006	−0.125*	−0.006	−0.111*
HbA1c (%)	−0.114	−0.409^#	−0.155	−0.490^#	−0.069	−0.366^#	−0.109	−0.491^#
sUA (μmol/L)	0.001	0.115^†	0.001	0.107^†	0.001	0.143^†	0.001	0.143^#
TG (mmol/L)	0.021	0.017	0.046	0.032	—	—	—	—
TC (mmol/L)	—	—	—	—	−0.052	−0.130	−0.074	−0.159
HDL (mmol/L)	−0.065	−0.029	−0.131	−0.052	—	—	—	—
LDL (mmol/L)	—	—	—	—	0.039	0.070	0.063	0.098
ALT (IU/L)	0.106	0.096*	0.117	0.094*	—	—	—	—
HOMA-IR	0.456	0.435^#	0.412	0.345^#	−0.275	−0.384^#	−0.309	−0.367^#
Male
Hypertension (yes = 1, no = 0)	−0.024	−0.016	−0.006	−0.004	—	—	—	—
Years from diagnosis	−0.017	−0.134^#	−0.026	−0.186^#	−0.014	−0.187^#	−0.023	−0.258^#
BMI (kg^2/cm)	0.026	0.116^#	0.024	0.100^†	—	—	—	—
SBP (mmHg)	—	—	—	—	0.001	0.034	0.001	0.021
DBP (mmHg)	—	—	—	—	−0.003	−0.056	−0.005	−0.086*
HbA1c (%)	−0.116	−0.395^#	−0.154	−0.474^#	−0.075	−0.423^#	−0.112	−0.526^#
sUA (μmol/L)	0.001	0.163^#	0.002	0.169^#	0.001	0.201^#	0.001	0.212^#
TG (mmol/L)	−0.026	−0.023	0.001	0.001	—	—	—	—
TC (mmol/L)	—	—	—	—	0.004	0.033	0.002	0.003
HDL (mmol/L)	−0.088	−0.034	−0.064	−0.022	—	—	—	—
LDL (mmol/L)	—	—	—	—	−0.036	−0.063	−0.021	−0.030
ALT (IU/L)	0.075	0.060*	0.083	0.060*	—	—	—	—
HOMA-IR	0.522	0.469^#	0.430	0.350^#	−0.202	−0.304^#	−0.283	−0.353^#

Β: partial regression coefficient; S-β: standard partial regression coefficient. All abnormally distributed continuous variables were log-transformed. Only parameters which were independently associated with β-cell function indices after multiple stepwise regression are shown. ^∗𝑃<0.05; ^†𝑃<0.01; ^#𝑃<0.001.