Evaluation of Hypoglycemic Efficacy of Tangningtongluo Formula, a Traditional Chinese Miao Medicine, in Two Rodent Animal Models

Figure 13

Pathological examination of fundus in db/db mice. (a) Fundus oculi from a normal mouse. (b) Retinopathy from db/db mice, featuring neuron loss and glioses in the ganglion cell layer. (c) Retinal lesions from metformin-treated db/db mouse. (d), (e), and (f) Mildly alleviated retinal lesions in the TNTL-treated db/db mouse at the dose of 3.6 g, 1.8 and 0.9 g/kg b.w., respectively.

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