Research Article
Comparative MicroRNA Expression Profiles of Cynomolgus Monkeys, Rat, and Human Reveal that miR-182 Is Involved in T2D Pathogenic Processes
Table 1
The physical indexes of the cynomolgus macaques.
| | No. | Sex | Age (year) | Weight (kg) | GLUa (mmol/L) | HBA1C (%) | Fasting insulin (uU/mL) | HDL-CH (mmol/L) | TG (mmol/L) | LDL-CH (mmol/L) | CHOL (mmol/L) | Comment |
| | 47 | M | 19 | 8.2 | 22.6 ± 2.9 | 10.0 ± 0.6 | 26.0 ± 3.0 | 1.1 ± 0.1 | 1.2 ± 0.1 | 1.7 ± 0.1 | 2.8 ± 0.2 | Intact T2D | | 64 | M | 18 | 6.9 | 17.0 ± 1.4 | 12.4 ± 1.5 | 7.7 ± 1.9 | 0.9 ± 0.1 | 2.1 ± 0.2 | 1.4 ± 0.7 | 2.9 ± 0.7 | Intact T2D | | 8 | F | 22 | 5.3 | 7.9 ± 1.8 | 6.1 ± 0.2 | 44.1 ± 11.0 | 1.3 ± 0.1 | 1.1 ± 0.0 | 1.1 ± 0.1 | 2.3 ± 0.4 | Intact T2D | | 52 | M | 18 | 9.2 | 2.8 ± 0.6 | 4.0 ± 0.0 | 26.9 ± 2.1 | 1.6 ± 0.0 | 0.3 ± 0.0 | 1.0 ± 0.1 | 2.5 ± 0.0 | Intact | | 61 | M | 17 | 7.7 | 2.8 ± 0.6 | 4.1 ± 0.0 | 15.9 ± 12.7 | 1.4 ± 0.1 | 0.4 ± 0.3 | 1.1 ± 0.0 | 2.4 ± 0.1 | Intact | | 1 | F | 18 | 6.1 | 3.5 ± 0.31 | 4.6 ± 0.2 | 30.7 ± 11.2 | 1.4 ± 0.0 | 1.3 ± 0.2 | 1.0 ± 0.3 | 2.5 ± 0.2 | Intact | | 11 | M | 12 | 11.1 | 8.6 ± 4.3 | 8.5 ± 0.1 | 356.1 ± 62.9 | 0.7 ± 0.2 | 4.4 ± 0.3 | 1.6 ± 0. 3 | 4.0 ± 0.5 | HFD T2D | | 25 | M | 9 | 11 | 12.7 ± 0.8 | 10.8 ± 1.6 | 229.2 ± 73.6 | 1.7 ± 0.1 | 1.1 ± 0.3 | 3.4 ± 1.8 | 5.0 ± 1.8 | HFD T2D | | 9 | M | 18 | 11.8 | 7.6 ± 1.5 | 6.7 ± 0.7 | 125.2 ± 78.4 | 1.8 ± 0.3 | 2.3 ± 0.2 | 2.6 ± 0.2 | 4.3 ± 0.6 | HFD T2D | | 31 | M | 12 | 11.5 | 3.2 ± 0.0 | 4.65 ± 0.2 | 361.9 ± 153.4 | 1.6 ± 0.1 | 2.1 ± 0.2 | 1.5 ± 0.2 | 3.6 ± 0.3 | HFD | | 34 | M | 13 | 9 | 3.1 ± 0.2 | 3.9 ± 0.1 | 107.8 ± 8.1 | 1.9 ± 0.0 | 0.4 ± 0.1 | 1.3 ± 0.0 | 3.0 ± 0.0 | HFD | | 6 | F | 21 | 6.5 | 4.6 ± 0.4 | 4.6 ± 0.3 | 115.6 ± 56.4 | 1.8 ± 0.1 | 0.7 ± 0.0 | 1.8 ± 0.2 | 3.7 ± 0.5 | HFD |
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GLU: glucose; HBA1C: glycosylated hemoglobin A1c; HDL-CH: high density lipoprotein cholesterol; TG: triglyceride; LDL-CH: low density lipoprotein cholesterin; CHOL: cholesterol.
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