Targets and Candidate Agents for Type 2 Diabetes Treatment with Computational Bioinformatics Approach

Table 2

Potential transcription factor targets.

TF target	value	TF target	value
hsa_V$RP58_01		hsa_V$SRF_Q6	0.0192
hsa_GGARNTKYCCA_UNKNOWN	0.0002	hsa_V$PITX2_Q2	0.0201
hsa_TTGTTT_V$FOXO4_01	0.0008	hsa_V$IRF_Q6	0.0201
hsa_V$CART1_01	0.0009	hsa_V$HNF1_C	0.0205
hsa_RYTGCNWTGGNR_UNKNOWN	0.0019	hsa_V$CEBPA_01	0.0205
hsa_TTAYRTAA_V$E4BP4_01	0.0021	hsa_GGGNNTTTCC_V$NFKB_Q6_01	0.0209
hsa_V$NFKB_Q6	0.0024	hsa_V$TAL1BETAE47_01	0.0209
hsa_RYAAAKNNNNNNTTGW_UNKNOWN	0.0027	hsa_V$CMYB_01	0.0214
hsa_V$NFKB_C	0.0027	hsa_V$HLF_01	0.0214
hsa_TATAAA_V$TATA_01	0.0041	hsa_V$CDC5_01	0.0218
hsa_V$CEBP_Q2	0.0052	hsa_V$TAL1ALPHAE47_01	0.0223
hsa_CTTTAAR_UNKNOWN	0.0054	hsa_V$RSRFC4_01	0.0223
hsa_V$FOXJ2_02	0.0057	hsa_V$CEBP_Q3	0.0232
hsa_V$SMAD3_Q6	0.0058	hsa_V$ICSBP_Q6	0.0252
hsa_TGGAAA_V$NFAT_Q4_01	0.0063	hsa_V$ZID_01	0.0267
hsa_CAGGTA_V$AREB6_01	0.0064	hsa_CCCNNNNNNAAGWT_UNKNOWN	0.0269
hsa_YTAAYNGCT_UNKNOWN	0.0071	hsa_V$RORA2_01	0.0291
hsa_V$FREAC4_01	0.0079	hsa_CAGGTG_V$E12_Q6	0.0293
hsa_V$ER_Q6_02	0.0084	hsa_V$GATA6_01	0.031
hsa_V$CEBPB_02	0.0092	hsa_V$E4BP4_01	0.0315
hsa_AAAYRNCTG_UNKNOWN	0.0096	hsa_V$CREB_Q4_01	0.0321
hsa_TAATTA_V$CHX10_01	0.0101	hsa_V$IK2_01	0.0328
hsa_TTANTCA_UNKNOWN	0.0106	hsa_V$CRX_Q4	0.0334
hsa_V$HNF4ALPHA_Q6	0.0113	hsa_GGATTA_V$PITX2_Q2	0.0347
hsa_V$ER_Q6_01	0.0118	hsa_V$ER_Q6	0.0352
hsa_CTGCAGY_UNKNOWN	0.0129	hsa_V$RSRFC4_Q2	0.0364
hsa_RNGTGGGC_UNKNOWN	0.0133	hsa_V$TATA_C	0.0371
hsa_V$HP1SITEFACTOR_Q6	0.0134	hsa_V$FAC1_01	0.0378
hsa_TGANTCA_V$AP1_C	0.0141	hsa_YKACATTT_UNKNOWN	0.0384
hsa_TGTYNNNNNRGCARM_UNKNOWN	0.0153	hsa_V$GATA1_05	0.0412
hsa_V$HNF1_01	0.018	hsa_WGTTNNNNNAAA_UNKNOWN	0.0413
hsa_CTTTGA_V$LEF1_Q2	0.0183	hsa_GTGGGTGK_UNKNOWN	0.0485