Relationship between Autonomic Nervous System Function and Continuous Interstitial Glucose Measurement in Patients with Type 2 Diabetes

Table 3

Correlation analysis between frequency-domain parameters of HRV, mean interstitial tissue glucose, and indices of glycemic variability.

Variable	Mean interstitial tissue glucose		MAGE		SD of mean glucose		M-value
	𝑟	𝑃	𝑟	𝑃	𝑟	𝑃	𝑟	𝑃
TP (t)	−0.25	0.09	−0.14	0.37	−0.29	0.052	−0.30	0.047
TP (n)	−0.25	0.09	−0.13	0.39	−0.29	0.047	−0.31	0.034
LF (t)	−0.19	0.22	−0.03	0.82	−0.14	0.35	−0.13	0.38
LF (n)	−0.20	0.19	−0.02	0.90	−0.14	0.36	−0.14	0.35
HF (t)	−0.08	0.59	0.05	0.76	−0.10	0.51	−0.16	0.29
HF (n)	−0.09	0.57	0.07	0.63	−0.09	0.56	−0.16	0.28
LF/HF (t)	−0.13	0.37	−0.11	0.46	−0.05	0.76	0.05	0.73
LF/HF (n)	−0.11	0.48	−0.12	0.44	−0.04	0.81	0.07	0.67

Data are adjusted for HbA1c and duration of diabetes.
All variables are log-transformed due to skewness.
(t): Total; (n): night
Night period: 23:00–06:00
TP: Variance of all normal-to-normal NN intervals
LF: Power in the low frequency range
HF: Power in the high frequency range
LF/HF: Ratio LF/HF.