Novel KIF6 Polymorphism Increases Susceptibility to Type 2 Diabetes Mellitus and Coronary Heart Disease in Han Chinese Men
Table 3
Associations of lipid levels with different genotypes of both genders.
Groups
TC
TG
HDL-C
LDL-C
Control
T2DM
T + CHD
Control
T2DM
T + CHD
Control
T2DM
T + CHD
Control
T2DM
T + CHD
Trp/Trp
4.45 ± 1.011
5.21 ± 1.31
5.69 ± 0.92
1.55 ± 0.69
2.71 ± 1.3
3.12 ± 1.36
1.41 ± 0.23
1.26 ± 0.17
1.16 ± 0.15
2.8 ± 0.76
2.85 ± 0.69
2.78 ± 0.74
Trp/Arg + Arg/Arg
4.49 ± 0.829
5.27 ± 1.17
5.75 ± 1.08
1.53 ± 0.75
2.97 ± 1.2
3.28 ± 1.5
1.35 ± 0.19
1.21 ± 0.27
1.12 ± 0.23
2.85 ± 0.74
2.99 ± 0.81
2.92 ± 0.8
Males
Trp/Trp
4.49 ± 1.02
5.26 ± 1.34
5.69 ± 0.99
1.55 ± 0.81
2.54 ± 1.12
2.98 ± 1.42
1.41 ± 0.19
1.25 ± 0.22
1.15 ± 0.16
2.86 ± 0.77
2.8 ± 0.72
2.82 ± 0.72
Trp/Arg + Arg/Arg
4.53 ± 0.91
5.34 ± 1.28
5.8 ± 1.11
1.62 ± 0.72
1.34 ± 0.22
1.09 ± 0.23
2.9 ± 0.75
3.04 ± 0.74
3.01 ± 0.81
Females
Trp/Trp
4.41 ± 1.00
5.16 ± 1.28
5.69 ± 0.85
1.55 ± 0.57
2.88 ± 1.48
3.26 ± 1.3
1.41 ± 0.27
1.27 ± 0.12
1.17 ± 0.14
2.76 ± 0.75
2.9 ± 0.66
2.74 ± 0.76
Trp/Arg + Arg/Arg
4.45 ± 0.74
5.2 ± 1.06
5.7 ± 1.05
1.44 ± 0.78
2.72 ± 1.15
3.1 ± 1.61
1.36 ± 0.16
1.27 ± 0.36
1.15 ± 0.23
2.8 ± 0.73
2.94 ± 0.88
2.83 ± 0.79
TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; T and T2DM, type 2 diabetes mellitus; CHD, coronary heart disease.
a, b versus the control.
