Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1

Table 2

Urinary protein identified in diabetes mellitus.

Serial number	Category of protein	Name of protein	Expression in diabetics
1	Defense response	α1-antitrypsin; Complement factor H, C3, B, I, C7, 9; Alpha-1-antichymotrypsin precursor; Antithrombin-III; Alpha-2-glycoprotein 1, zinc; Ig gama 1 chain C region; Alpha and beta-2-microglobulin; Alpha-2-antiplasmin precursor; Vitronectin precursor	+; +; +; +; +; +; +; +; +
2	Transport	Serotransferrin precursor; Ceruloplasmin precursor; Hemopexin; AMBP protein; Albumin; Haptoglobin precursor; Transthyretin precursor; VDBP	−; +; +; +; −; +; −; −
3	Metabolism	ApoA-1, ApoA-II precursor, Apo-D; Alpha-1B-glycoprotein; Beta-2-glycoprotein 1 precursor; Prostaglandin H2 D-isomerase precursor; Alpha-2-HS-glycoprotein precursor; E-cadherin; Dystroglycan precursor; Fibrinogen beta chain precursor	−; +; +; +; +; +; +; +
4	Signal transduction	Kininogen precursor; B-factor, properdin; Clusterin; Angiotensinogen; Sulfated glycoprotein 2; retinol-binding protein 4; Epidermal growth factor	+; +; −; +; +; +; +
5	Cell development	Lumican precursor	+