Determining Predictors of Early Response to Exenatide in Patients with Type 2 Diabetes Mellitus

Table 2

Mean (±SD) weight, BMI, and HbA1c at baseline, 3 months, and 6 months within responders ( = 63) and nonresponders ( = 49). The overall value reflects the significance before adjustment and adjusted value denotes the significance between time points following Tukey’s test for multiple comparisons.

Parameter	Responders			Overall value	Adjusted value
	Baseline	3 months	6 months		Baseline to 3 months	Baseline to 6 months	3 months to 6 months
Weight (kg)	114 ± 18.6	109 ± 19.1	106 ± 20.6	<0.001	<0.001	<0.001	<0.001
BMI (kg/m^2)	39.4 ± 5.63	37.6 ± 5.91	36.5 ± 6.57	<0.001	<0.001	<0.001	<0.001
HbA1c (mmol/mol)	85.1 ± 15.4	67.8 ± 13.4	60.7 ± 12.2	<0.001	<0.001	<0.001	<0.001
Parameter	Nonresponders			Overall value	Adjusted value
	Baseline	3 months	6 months		Baseline to 3 months	Baseline to 6 months	3 months to 6 months
Weight (kg)	111 ± 16.3	108 ± 16.9	106 ± 16.8	<0.001	<0.001	<0.001	<0.001
BMI (kg/m^2)	38.4 ± 5.7	37.7 ± 5.97	37.1 ± 6	<0.001	<0.001	<0.001	<0.001
HbA1c (mmol/mol)	75.5 ± 11.4	73.7 ± 12.9	77 ± 13.2	0.028	0.29	0.42	0.032

BMI: body mass index; HbA1c: glycated haemoglobin.