Treatment with α-Lipoic Acid over 16 Weeks in Type 2 Diabetic Patients with Symptomatic Polyneuropathy Who Responded to Initial 4-Week High-Dose Loading

Table 4

Percentages (95% CI) of patients who required analgesic rescue medication.

Week from randomization	-Lipoic acid treatment	-Lipoic acid withdrawal	value
	% (95% CI)	% (95% CI)
Week 4	12.5 (2.3–34.4)	17.6 (5.0–39.6)	NS
Week 8	25.0 (9.0–48.4)	35.3 (16.6–58.0)	NS
Week 12	18.8 (5.3–41.7)	52.9 (31.1–74.0)
Week 16	25.0 (9.0–48.4)	52.9 (31.1–74.0)