Rat Models of Diet-Induced Obesity and High Fat/Low Dose Streptozotocin Type 2 Diabetes: Effect of Reversal of High Fat Diet Compared to Treatment with Enalapril or Menhaden Oil on Glucose Utilization and Neuropathic Endpoints

Figure 1

Effect of treatment of diet induced obese rats (a) and high fat fed/low dose streptozotocin type 2 diabetic rats (b) with normal diet, enalapril, or menhaden oil on glucose tolerance. Glucose tolerance was determined as described in Section 2. Data are presented as the mean ± S.E.M. in mg/dl. The number of rats in each group was the same as shown in Table 1. Control rats (C), diet induced obese rats (HF), diabetic rats (HF STZ), and rats returned to a normal diet or treated with enalapril or placed on a menhaden oil enriched diet designated as Rev, Enal, or MO, respectively.

(a)

(b)