Renal Kallikrein Activation and Renoprotection after Dual Blockade of Renin-Angiotensin System in Diet-Induced Diabetic Nephropathy

Table 2

Expression of kallikrein 1 in renal tissue.

Group	The number of samples	Kallikrein 1 integral optical density value
1	10	9.392 ± 0.597
2	7	21.839 ± 4.686^*
3	10	30.312 ± 7.700^*#
4	9	31.717 ± 5.147^*#
5	8	46.119 ± 5.385^*#◆▼

Group 1, normal control group; group 2, diabetic nephropathy control group; group 3, benazepril (10 mg/kg/d); group 4, irbesartan (30 mg/kg/d); and group 5, benazepril (10 mg/kg/d) & irbesartan (30 mg/kg/d); and compared with group 1, ^*; compared with group 2, ^#; compared with group 3, ^◆; compared with group 4, ^▼.