Effects of High Glucose Levels and Glycated Serum on GIP Responsiveness in the Pancreatic Beta Cell Line HIT-T15

Figure 5

Treatments with GS and HG altered insulin secretion. Relative levels of intracellular insulin content (a) and insulin released in the supernatants of HIT-T15 cells challenged for 2 hours in the presence of 4 mmol/L glucose alone (b) or 10 nmol GIP (c). Data are expressed as mean ± SE versus CTR (). and versus CTR.

(a)

(b)

(c)