A Cross-Sectional Study Demonstrating Increased Serum Amyloid A Related Inflammation in High-Density Lipoproteins from Subjects with Type 1 Diabetes Mellitus and How This Association Was Augmented by Poor Glycaemic Control
Table 1
Subject characteristics for comparison 1 and comparison 2.
Characteristic
Comparison 1
Comparison 2
Control group ()
T1DM group ()
-test
T1DM group HbA1c <8.34% ()
T1DM group HbA1c ≥8.34% ()
-test
BMI (kg/m2)
26.4 (3.5)
26.0 (3.9)
0.686
25.0 (3.5)
27.0 (4.1)
0.062
Age (years)
39.4 (10.1)
35.8 (8.3)
0.095
36.8 (9.1)
35.0 (7.5)
0.451
Gender (male : female)
17 : 32
18 : 32
0.836
9 : 15
9 : 17
0.836
Fasting glucose (mmol/L)
5.05 (4.60, 5.30)
9.89 (6.30, 14.60)
≤0.001
9.05 (5.20, 12.80)
10.63 (6.58, 14.85)
0.279
HbA1C (%)
5.3 (5.1, 5.5)
8.3 (7.4, 8.8)
≤0.001
7.4 (6.8, 8.0)
9.2 (8.6, 9.7)
≤0.001
HbA1c (mmol/mol)
34 (32, 37)
68 (57, 72)
≤0.001
57 (51, 64)
76 (70, 83)
≤0.001
Total cholesterol (mmol/L)
4.92 (0.86)
4.60 (0.84)
0.065
4.36 (0.83)
4.83 (0.80)
0.048
Triglycerides (mmol/L)
1.31 (0.77)
1.04 (0.39)
0.050
0.98 (0.34)
1.09 (0.44)
0.330
HDL cholesterol (mmol/L)
1.41 (0.34)
1.50 (0.41)
0.204
1.43 (0.52)
1.57 (0.28)
0.231
LDL cholesterol (mmol/L)
2.99 (0.84)
2.62 (0.68)
0.032
2.48 (0.57)
2.75 (0.76)
0.157
Statin therapy (number)
0
5
NA
1
4
NA
ACE Inhibitors (number)
0
5
NA
2
3
NA
Results expressed as mean (SD) or when data was not normally distributed as geometric mean (interquartile range).
