Research Article

A Cross-Sectional Study Demonstrating Increased Serum Amyloid A Related Inflammation in High-Density Lipoproteins from Subjects with Type 1 Diabetes Mellitus and How This Association Was Augmented by Poor Glycaemic Control

Table 2

Serum hsCRP and Serum, HDL2 and HDL3 SAA concentration.

AnalyateComparison 1Comparison 2
Control group ()T1DM group ()-testT1DM group HbA1c <8.34% ()T1DM group HbA1c ≥8.34% ()-test

Serum-hsCRP (mg/L)1.97 (1.00, 2.38)2.89 (1.00, 4.40)0.1622.56 (1.00, 2.30)3.24 (1.30, 4.93)0.355
Serum-SAA (g/L)16241 (7275, 17645)23837 (8133, 40737)0.08815885 (8060, 18945)30706 (7984, 47986)0.031
Protein-standardised SAA
 HDL2 (µg/mg protein)3.00 (0.97, 4.12)5.63 (1.65, 7.63)0.0034.97 (1.41, 4.42)6.23 (2.06, 9.94)0.096
 HDL3 (µg/mg protein)3.48 (1.37, 3.55)5.95 (2.31, 9.57)0.0054.50 (1.18, 5.01)7.34 (2.35, 12.29)0.028
Nonprotein standardised SAA
 HDL2 (µg/L)690 (242, 951)1674 (379, 1990)0.0041260 (357, 1408)2055 (541, 2589)0.085
 HDL3 (µg/L)8951 (3326, 8966)15972 (4625, 23331)0.00510362 (3883, 13315)21151 (6846, 33534)0.019

Results expressed as mean (SD) or when data was not normally distributed as geometric mean (interquartile range).