Journal of Diabetes Research / 2015 / Article / Fig 1

Research Article

Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process

Figure 1

Schematic diagram of the mevalonate pathway. HMGR, 3-hydroxy-3-methylglutaryl-coenzyme A reductase; FPPS, farnesyl pyrophosphate synthase; SQS, squalene synthase; FNT, farnesyltransferase; GGT-1, geranylgeranyltransferase-1; GGPPS, geranylgeranyl pyrophosphate synthase.