Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process
Histological analysis of aortas. (a) Lesion areas (LA) of aorta from BALB/c mice at 0-, 8-, and 16-week diabetic duration. (b) Media thickness (MT) of the thoracic aorta from BALB/c mice at 0-, 8-, and 16-week diabetic duration. Data were obtained from 6 mice for each group. Data expressed as mean ± SEM. versus age-matched control mice; versus age-matched control mice.