Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes

Figure 11

(a) The upper panel shows the graphic representation of the progression of both fasting and postmeal hyperglycemia. The lower panel demonstrates both insulin resistance and defective beta-cell function (Natural History of Type 2 Diabetes © 2010, International Diabetes Center, Minneapolis, MN, USA, used with permission). (b) demonstrates the similarity between the progression of diabetes between the human condition and ZDSD rat. The vertical dotted line represents the onset of diabetes.

(a)

(b)