Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease
(a) Quantitative results of retinal blood vessel leakage by Evans blue dye. Data are expressed as means ± SD (). compared to control; ### compared to DM without DC. (b) Retinal mRNA expression of occludin (Ocln), ZO-1 (Tjp1), claudin-1 (Cldn1), and claudin-5 (Cldn5). Data are expressed as means ± SD ( for control, for DM, for DM+DC 30 mg/kg, and for DM+DC 300 mg/kg). , compared to control; #, ## compared to DM without DC. (c) Retinal protein expression of occludin and claudin-1 is detected by immunoblotting using specific antibodies. The occludin protein represents four independent experiments, and claudin-1 protein represents two independent experiments.