[Retracted] Small Molecule Kaempferol Promotes Insulin Sensitivity and Preserved Pancreatic β-Cell Mass in Middle-Aged Obese Diabetic Mice

Figure 1

Kaempferol supplementation had no significant effects on food consumption but reduced body weight gain and fat mass in HF diet-fed middle-aged mice. (a) Food intake was recorded twice a week and the average daily food intake was calculated. (b) Body weight of the individual mouse was measured each week. Data shown are the average body weight of last week of feeding experiment. Body composition including fat mass (c) and lean mass (d) was measured following 5 mo of standard diet or HF feeding. At the end of the experiment, fasting plasma total cholesterol (e), LDL-cholesterol (f), triglycerides (g), and HDL-cholesterol (h) were measured in duplicated samples by using mouse ELISA kits. Data are shown as means ± SE (). versus standard diet-fed mice (C); versus HF-fed mice. C: standard diet; HF: high-fat diet; HF + K1: HF diet containing 0.01% kaempferol; HF + K2: HF diet supplemented with 0.05% kaempferol.

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