Research Article

Diabetes Complications at Presentation and One Year by Glycated Haemoglobin at Diagnosis in a Multiethnic and Diverse Socioeconomic Population: Results from the South London Diabetes Study

Table 1

Comparisons between participants diagnosed with HbA1c < 48 mmol/mol and with HbA1c ≥ 48 mmol/mol at diagnosis and recruitment.

with dataHbA1c < 48 mmol/mol (6.5%)HbA1c ≥ 48 mmol/mol (6.5%) value

Demographical data
Age148858.73 (±10.36)54.87 (±11.07)<0.0001
Gender (% male)1488188 (55.46)632 (55.00)0.8829
Ethnicity (%)1488
 White218 (64.31)528 (45.95)<0.0001
 Black98 (28.91)491 (42.73)
 Asian23 (6.78)130 (11.31)

Median (IQR) HbA1c at diagnosis
HbA1c (mmol/mol)148844.26 (42.08–45.35),58.47 (51.91–82.52)<0.0010
HbA1c (%)6.20 (6.00–6.30)7.50 (6.90–9.70)

Cardiovascular risk factors (SD) at diagnosis
LDL-C (mmol/L)12112.86 (±0.98)3.67 (±21.83)0.5313
HDL-C (mmol/L)12511.28 (±0.67)1.24 (±0.44)0.1750
Total cholesterol (mmol/L)13574.70 (±1.32)4.90 (±1.50)0.0053
Triglycerides (mmol/L)12731.40 (±0.85)1.59 (±1.29)0.0001
BMI (kg/m2)138030.77 (±7.74)31.60 (8.40)0.0035
BPS (mmHg)1409133.96 (±16.84)134.65 (±16.28)0.5087
BPD (mmHg)140980.00 (±11.00)82.00 (±12.00)<0.0001

Complication status, HbA1c medication status at recruitment
Retinopathy (%)133530 (9.43)80 (7.86)0.3749
Microalbuminuria (%)123737 (12.76)158 (16.68)0.1279
Sensory neuropathy (%)136832 (10.16)70 (6.65)0.0393
MI (%)148224 (7.08)55 (4.81)0.1026
Stroke (%)14798 (2.37)40 (3.50)0.3042
HbA1c (mmol/mol)139542.08 (38.80–44.26)50.82 (45.35–60.65)<0.0001
HbA1c (%)6.00 (5.70–6.20)6.80 (6.30–7.40)
Receiving insulin (%)14816 (1.78)43 (3.76)0.0743
Receiving oral diabetes agents (%)147097 (29.1)704 (61.9)<0.0001