Polysaccharides from Enteromorpha prolifera Improve Glucose Metabolism in Diabetic Rats

Table 2

The effect of PEP on FBG levels in DM rats.

Group	FBG (mg/dL)
	Day 0	Day 7	Day 14	Day 21	Day 28
Control	155.34 ± 35.1	176.76 ± 38.52	161.64 ± 27.18	161.10 ± 29.88	138.78 ± 28.62
Model	321.48 ± 46.1^#	258.48 ± 35.82^#	248.76 ± 39.60^#	283.68 ± 37.98^#	258.12 ± 58.68^#
Metformin HC	328.86 ± 14.58	148.32 ± 15.66	151.38 ± 16.38	153.18 ± 16.38	150.48 ± 19.08
150 mg/kg PEP	297.36 ± 40.86^#	180.72 ± 19.62	167.76 ± 41.40	194.76 ± 34.02	162.00 ± 33.30
300 mg/kg PEP	291.42 ± 36.54^#	159.48 ± 28.26	152.28 ± 36.90	172.08 ± 38.88	149.04 ± 34.56
600 mg/kg PEP	325.08 ± 44.64^#	175.14 ± 26.10	160.74 ± 29.16	173.34 ± 31.32	158.76 ± 37.80

A DM model was established by feeding rats a high-fat diet and injecting them with a low dose of STZ. After the model was established, PEP (150, 300, and 600 mg/kg) was administered intragastrically for 28 d. Blood samples from the caudal vein were collected to determine FBG levels using a blood glucose meter. The data are presented as the mean ± standard deviation ( rats). Compared with the model group: ; compared with the control group: ^#; compared with day 0: ^&.