Polysaccharides from Enteromorpha prolifera Improve Glucose Metabolism in Diabetic Rats

Table 4

The effect of PEP on MDA, SOD, and GSH-Px in DM rats.

Group	MDA (nmol/mL)	SOD (U/mL)	GSH-Px (mol/L)
Control	5.09 ± 0.63	252.68 ± 24.92	4800.00 ± 449.46
Model	5.94 ± 0.89^#	243.45 ± 19.32	3680.00 ± 388.65^#
Metformin HC	5.05 ± 0.51	239.90 ± 28.09	4164.57 ± 589.16
150 mg/kg PEP	5.03 ± 0.45	271.31 ± 23.37	3979.43 ± 397.13^#
300 mg/kg PEP	4.25 ± 0.67	272.63 ± 22.25	4132.57 ± 483.74
600 mg/kg PEP	4.56 ± 0.96	269.09 ± 26.05	4304.00 ± 341.72

A DM model was established by feeding rats a high-fat diet and injecting them with a low dose of STZ. After the model was established, PEP (150, 300, and 600 mg/kg) was administered intragastrically as an intervention for 28 d. Blood samples from angular vein were collected to quantitate the enzymatic activity of MDA (nmol/mL), SOD (U/mL), and GSH-Px (mol/L) in serum. The data are presented as the mean ± standard deviation ( rats). Compared with the model group: ; compared with the control group: ^#.