Research Article
Healthy Chilean Adolescents with HOMA-IR ≥ 2.6 Have Increased Cardiometabolic Risk: Association with Genetic, Biological, and Environmental Factors
Table 1
Background characteristics of adolescents in the sample by insulin sensitivity (
).
| | HOMA-IR < 2.6 () | HOMA-IR ≥ 2.6 () | Total sample | valuec |
| Age (years) | 16.8 ± 0.3a | 16.9 ± 0.2 | 16.8 ± 0.3 | n.s. | Anthropometrics | | | | | BMI ( score) | 0.48 ± 1.1 | 1.53 ± 1.2 | 0.65 ± 1.2 | <0.001 | WC (cm) | 79.4 ± 9.9 | 90.4 ± 14.3 | 81.2 ± 11.4 | <0.001 | Lean Mass (%) | 68.7 ± 11.4 | 62.0 ± 9.4 | 67.6 ± 11.1 | <0.001 | Fat mass (%) | 27.9 ± 10.7 | 34.7 ± 9.4 | 29.0 ± 10.8 | <0.001 | BMI ≥ 2 SD | 52 (9.3)b | 44 (40.4) | 96 (14.4) | <0.001d | CVM profile | | | | | SBP (mm Hg) | 111.1 ± 10.2 | 118.3 ± 10.7 | 112.2 ± 10.6 | <0.001 | DBP (mm Hg) | 68.7 ± 7.0 | 72.1 ± 6.5 | 69.3 ± 7.0 | <0.001 | TG (mg/dL) | 82.5 ± 45.5 | 118.2 ± 71.6 | 88.3 ± 50.1 | <0.001 | HDL-chol (mg/dL) | 40.8 ± 10.6 | 36.6 ± 10.2 | 40.1 ± 10.6 | <0.001 | Glucose (mg/dL) | 87.4 ± 8.8 | 94.2 ± 10.8 | 88.6 ± 9.5 | <0.001 | Insulin (µIU/dL) | 6.3 ± 2.5 | 17.5 ± 7.0 | 8.1 ± 5.5 | <0.001 | hs-CRP (mg/L) | 0.95 ± 1.9 | 1.10 ± 1.6 | 0.98 ± 1.9 | n.s. | Adiponectin (µg/mL) | 12.3 ± 5.5 | 9.2 ± 5.1 | 11.8 ± 5.5 | <0.001 | Lifestyles habits | | | | | Unhealthy eating | 139 (24.9) | 20 (18.4) | 159 (23.8) | n.s. | Physical inactivity | 209 (37.4) | 56 (51.4) | 265 (39.7) | 0.006d |
|
|
Mean ± S.D; b (%); cStudent’s -test, except as indicated. dChi2 (Pearson).
|