Research Article

Healthy Chilean Adolescents with HOMA-IR 2.6 Have Increased Cardiometabolic Risk: Association with Genetic, Biological, and Environmental Factors

Table 1

Background characteristics of adolescents in the sample by insulin sensitivity ().

HOMA-IR < 2.6 
()
HOMA-IR ≥ 2.6 
()
Total sample valuec

Age (years)16.8 ± 0.3a16.9 ± 0.216.8 ± 0.3n.s.
Anthropometrics
 BMI ( score)0.48 ± 1.11.53 ± 1.20.65 ± 1.2<0.001
 WC (cm)79.4 ± 9.990.4 ± 14.381.2 ± 11.4<0.001
 Lean Mass (%)68.7 ± 11.462.0 ± 9.467.6 ± 11.1<0.001
 Fat mass (%)27.9 ± 10.734.7 ± 9.429.0 ± 10.8<0.001
 BMI ≥ 2 SD52 (9.3)b44 (40.4)96 (14.4)<0.001d
CVM profile
 SBP (mm Hg)111.1 ± 10.2118.3 ± 10.7112.2 ± 10.6<0.001
 DBP (mm Hg)68.7 ± 7.072.1 ± 6.569.3 ± 7.0<0.001
 TG (mg/dL)82.5 ± 45.5118.2 ± 71.688.3 ± 50.1<0.001
 HDL-chol (mg/dL)40.8 ± 10.636.6 ± 10.240.1 ± 10.6<0.001
 Glucose (mg/dL)87.4 ± 8.894.2 ± 10.888.6 ± 9.5<0.001
 Insulin (µIU/dL)6.3 ± 2.517.5 ± 7.08.1 ± 5.5<0.001
 hs-CRP (mg/L)0.95 ± 1.91.10 ± 1.60.98 ± 1.9n.s.
 Adiponectin (µg/mL)12.3 ± 5.59.2 ± 5.111.8 ± 5.5<0.001
Lifestyles habits
 Unhealthy eating139 (24.9)20 (18.4)159 (23.8)n.s.
 Physical inactivity209 (37.4)56 (51.4)265 (39.7)0.006d

Mean ± S.D; b (%); cStudent’s -test, except as indicated. dChi2 (Pearson).