Review Article

Updates in the Management of Diabetic Macular Edema

Table 1

Grading of foveal avascular zone using fluorescein angiography. *As defined in the ETDRS group report 11.

GradeOutline of FAZSize of FAZCapillary loss

Grade 0Outline of FAZ normalSize of FAZ less than the area of the 300 µm radius circle*Capillary loss absent

Grade 1Outline of FAZ not smoothly round or oval-shaped. Appreciable irregularities seen but not necessarily abnormalSize of FAZ equal to area of the 300 µm radius circle*Capillary loss questionable

Grade 2Outline of FAZ obviously damaged but limited to less than half of the circumferenceSize of FAZ greater than the 300 µm radius circle* but less than the 500 µm radius circle*Capillary loss definitely present

Grade 3Outline of FAZ destroyed for at least half the circumference, with some remnants still presentSize of FAZ greater than or equal to the 500 µm radius circle*Moderate capillary loss

Grade 4Capillary outline totally destroyedSevere capillary loss

Grade 8Cannot be gradedCannot be graded