In Vitro and In Vivo Effects of Metformin on Osteopontin Expression in Mice Adipose-Derived Multipotent Stromal Cells and Adipose Tissue

Figure 12

The concentration of OPN protein in the serum of mice derived from control and experimental-metformin treated group. Mean values express osteopontin level of nine mice belonging to the investigated group. The statistically significant decrease of OPN protein was noted in serum of experimental animals. The statistically significant difference determined in relation to the results obtained for control group was indicated with asterisks ().