Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice

<div>E2HSA exhibits GLP-1 receptor activating efficacy in NIT-1 cells. NIT-1 cells transiently transfected with Peak12 RIP-CRE 6x Luciferase reporter gene plasmid were treated with indicated concentrations of E2HSA and exendin-4 for 24 hours. Luciferase expression in cell lysates was measured by chemiluminescence. Data obtained were used to calculate the activation fold at different concentrations. Values are expressed as means ± S.E.M and are representative of data from two independent experiments, each performed in quadruplicate.</div>

Journal of Diabetes Research

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Figure 1

Figure 1: Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice 

Figure 1 | Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice 