Genetic Associations of PPARGC1A with Type 2 Diabetes: Differences among Populations with African Origins

Table 1

Characteristics of PPARGC1A SNPs.

NCBI ref SNP number^*	Chromosome nucleotide position^‡	MAF^†	Disease risk associations	-score
rs8192678	23815662	0.291	T2D, CVD, Obesity	0.50
rs7656250	23866016	0.265	T2D, CVD	0.27
rs4235308	23864412	0.396	CVD	0.28
rs11724368	99418507	0.106	CVD	0.25

Note: ^*National Center for Biotechnology Information (NCBI) reference single nucleotide polymorphism (SNP) number (http://www.ncbi.nlm.nih.gov/).
^‡Genome Reference Consortium Human Build 37 patch release 13 (GRCh37.p13) used for nucleotide position (http://www.ncbi.nlm.nih.gov/SNP/).
^†Minor allele frequencies are from a global population genotyped in HapMap project.
MAF: minor allele frequency; T2D: type 2 diabetes; CVD: cardiovascular disease; -Score: functionality score.