Table 3: Genotype distribution of PPARGC1A SNPs by ethnicity and T2D.

SNPsMinor alleleHaitian Americans (n = 226)African Americans (n = 246)
Cases (n = 110)Controls (n = 116)-valueMAF (%)Cases (n = 124)Controls (n = 122) valueMAF (%)
CasesControlsCasesControls

Genotype frequencies (, %)
 rs8192678
  CC 92 (84)102 (88)103 (84)104 (85)
  CTT4 (4)14 (12)0.0000.1450.06019 (15)18 (15)0.3650.0930.074
  TT14 (13)0 (0)2 (2)0 (0)
 rs7656250
  TT85 (73)96 (83)90 (72)98 (80)
  CTC24 (22)19 (16)0.5790.1180.09027 (22)21 (17)0.2630.1650.110
  CC1 (0.9)1 (0.8)7 (6)3 (2)
 rs4235308
  TT35 (32)52 (45)56 (45)51 (42)
  CTC59 (54)52 (45)0.1240.4410.32751 (41)60 (49)0.3270.3430.336
  CC16 (14)12 (10)17 (14)11 (9)
 rs11724368
  CC93 (84)100 (86)103 (83)105 (86)
  CGG17 (15)16 (14)0.7240.0720.06919 (15)17 (14)0.3470.0930.069
  GG0 (0)0 (0)2 (2)0 (0)

Note: genotype frequencies are depicted as (%). Cases: with T2D; controls: without T2D; SNP: single nucleotide polymorphism; MAF: minor allele frequency.