MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue

Figure 1

miR-223 expression in human AT. (a) Depicted is comparison of the levels of miR-223 expression in the AT of women with and without IR; miR-223 was significantly overexpressed in the IR group. (b) Depicted is comparison of the levels of miR-223 expression in the AT of women with and without PCOS; the expression of miR-223 did not differ between two groups. (c) Depicted is comparison of the levels of miR-223 expression in the AT of women: (A) without PCOS or IR, (B) without PCOS (non-PCOS), but with IR, (C) with PCOS and IR, and (D) with PCOS, but without IR; the expression of miR-223 was significantly higher in the AT in women with IR. comparing tissues from women with or without PCOS and with IR versus that of women without PCOS or IR. (d) Depicted is the association between miR-223 expression and HOMA-IR. (Two group comparisons, (a) and (b), were carried out by unpaired Student’s -test; comparison of (d) was carried out by ANOVA followed by a posttest by using the Fisher (among groups) and Dunnett (compared to control group) test.)

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