Charge-Based Inhibitors of Amylin Fibrillization and Toxicity

Figure 9

Salt-dependence on the effectiveness of charge-loaded analogs for the inhibition of 20 M WT-amylin fibrillization. Fibril elongation rates with Arg-1 (a), Arg-2 (b), Mem-T (c), and lag times with Mem-T (d).

(a)

(b)

(c)

(d)