GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance
Table 1
Baseline characteristics of the patient and control groups.
IGT ()
NGT ()
Age (years)
49.21 ± 10.72
47.45 ± 12.09
0.526
Gender (F/M)
24/13
21/11
0.999
BMI (kg/m2)
33.04 ± 7.75
31.06 ± 4.68
0.20
Hb (g/L)
14.14 ± 1.15
14.01 ± 1.10
0.617
Ferritin (ng/mL)
80.60 ± 76.50
66.81 ± 41.21
0.365
Fasting glucose (mg/dL)
106.0 [99.50–116.0]
92.0 [88.25–97.0]
<0.001
Fasting insulin (μIU/mL)
14.92 ± 7.99
11.89 ± 6.64
0.109
HOMA-IR
3.95 ± 2.21
2.75 ± 1.49
0.012
AUC-G (mg/dL/min)
22002.97 ± 2917.88
14627.0 ± 2932.26
<0.001
Creatinine (mg/dL)
0.79 ± 0.20
0.74 ± 0.18
0.261
GFR (mL/min per 1.73 m2)
101.97 ± 27.42
107.70 ± 23.71
0.539
UA (mg/dL)
5.48 ± 1.55
4.84 ± 1.36
0.076
IL-6 (pg/mL)
1.24 [0.94–1.64]
1.07 [0.92–1.57]
0.270
hsCRP (mg/dL)
0.32 [0.15–0.73]
0.20 [0.11–0.48]
0.135
Hepcidin (ng/mL)
25.89 ± 15.60
26.94 ± 13.05
0.767
GDF-15 (pg/mL)
897.93 [691.57–1616.10]
770.36 [535.34–1040.04]
0.026
Normally distributed variables are presented as mean ± standard deviation and non-normally distributed variables are presented as median [25th, 75th percentile]. AUC-G: area under the curve for glucose, GFR: glomerular filtration rate, hsCRP: high sensitivity C-reactive protein, IGT: impaired glucose tolerance, NGT: normal glucose tolerance, BMI: body mass index, and UA: uric acid.
