Research Article

Exenatide Treatment Causes Suppression of Serum Ghrelin Levels following Mixed Meal Test in Obese Diabetic Women

Table 3

Percentage changes in serum glucose, insulin, and ghrelin levels at 60, 120, and 180 minutes following mixed meal test with and without exenatide usage.

Percentage change (%)Time (minute)With exenatide (mean ± SD)Without exenatide (mean ± SD)

Glucose600.37 ± 0.250.50 ± 0.130.032
1200.20 ± 0.230.49 ± 0.16<0.001
180−0.17 ± 0.240.36 ± 0.170.005

Insulin602.12 ± 0.982.74 ± 1.450.08
1203.88 ± 2.505.93 ± 2.620.001
1801.50 ± 1.212.21 ± 0.900.027

Ghrelin60−0.07 ± 0.130.10 ± 0.330.074
120−0.07 ± 0.20−0.04 ± 0.510.221
180−0.20 ± 0.150.10 ± 0.290.001

SD: standard deviation.