JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression

Figure 1

JNK isoform expression in INS-1 cell. INS-1 cells were exposed to 150 pg/mL IL-1β (square) or vehicle (circle) for 2 to 24 h. Relative mRNA of the JNK isoforms was measured using quantitative RT-PCR and normalized to the average of 18S and hprt1. (a) Relative JNK1α1 mRNA expression, (b) relative JNK1β1 mRNA expression, (c) relative JNK2α1 mRNA expression, (d) relative JNK2β2 mRNA expression, (e) relative JNK3α1 mRNA expression, and (f) relative JNK3α2 mRNA expression. Data are means ± SEM of independent experiments. , , and .

(a)

(b)

(c)

(d)

(e)

(f)