Clinical Study

Screening of Undiagnosed Hypothyroidism in Elderly Persons with Diabetes according to Age-Specific Reference Intervals for Serum Thyroid Stimulating Hormone and the Impact of Antidiabetes Drugs

Table 1

Baseline data of all subjects studied: number, age, body mass index, fasting glucose, and glycated hemoglobin in patients with diabetes and persons without diabetes.

DataPatients with diabetesPersons without diabetes values

Males/females (/%)332 (44.2%)/419 (55.8%) 176 (43.0%)/233 (57.0%)

Age (years) 71.3 ± 7.069.9 ± 7.6 NS

BMI (kg/m2)28.3 ± 5.327.5 ± 5.80.044

FG (nmol/L)
 Median7.64.60.008
 25–75%5.5–10.64.1–5.3
 95% CI7.2–9.84.3–5.6

HbA1c (% total Hb)
 Median7.25.20.0003
 25–75%6.0–9.25.1–5.6
 95% CI6.8–8.85.1–5.4

BMI: body mass index; FG: fasting glucose; HbA1c: glycated haemoglobin; 25–75%: 25–75 percentiles; CI: confidence interval. For converting FG in mg/dL, multiply nmol/L by 18; for converting HbA1c in % to IFCC mmol/mol, use the equation (10.93 × NGSP) − 23.50.