Table 3: TSH and FT4 in subgroups of euthyroid patients with diabetes.

Subgroups of antidiabetes drugs values
MTFSU/DPP4/TZDINSMTF+

TSH (mU/L)
 Median2.83.34.13.2MTF × other groups < 0.05
INS × other groups < 0.05
 25–75%2.4–3.52.8–3.93.6–5.32.4–4.7
 95% CI2.9–3.42.9–3.64.4–6.53.0–4.3

FT4 (pmol/L)
 Mean14.214.415.414.2NS
 SD±0.5±0.9±2.6±2.6
 95% CI12.9–16.710.3–15.412.9–16.714.2–15.4

TSH: thyroid stimulating hormone; FT4: free thyroxine; 25–75%: 25–75 percentiles CI: confidence interval; NS: not significant. MTF: metformin; SU/DPP4/TZD: sulfonylureas, dipeptidyl peptidase 4 (DPP4) inhibitors, and thiazolidinedione analyzed together. For converting FT4 in nd/dL, multiply pmol/L by 0.078.