Vascular Endothelial Growth Factor Gene Polymorphism (rs2010963) and Its Receptor, Kinase Insert Domain-Containing Receptor Gene Polymorphism (rs2071559), and Markers of Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus

Table 4

Comparison of markers of carotid atherosclerosis (presence of carotid plaques, presence of unstable plaques) in subjects with T2DM at the beginning of the study with regard to the rs2010963 and rs2071559 genotypes.

	rs2010963				rs2071559
	CC (52)	CG (280)	GG (263)		CC (131)	TC (309)	TT (155)
Presence of carotid plaques (%)	46 (88.5)	229 (81.8)	223 (84.7)		117 (89.3)	250 (80.9)	133 (85.8)
OR (95% CI)		0.68; (0.46–2.57)	0.72; (0.41–1.26)	0.45		0.57; (0.53–2.06)	0.68; (0.34–1.34)	0.15
^†	—	0.70	0.24		—	0.59	0.26
Presence of unstable carotid plaques (%)	27 (51.9)	143 (51.1)	121 (46.0)		69 (52.7)	142 (46.0)	77 (49.7)
OR (95% CI)		1.09; (0.22–3.66)	0.97; (0.38–2.50)	0.45		0.55; (0.14–2.18)	0.67; (0.20–2.26)	0.42
^†	—	0.56	0.59		—	0.39	0.51

Reference genotype is CC.
^† value for logistic regression analysis.