Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy

Figure 1

Blood glucose levels and nephromegaly. Nonfasting blood glucose levels in nondiabetic control (Control), diabetic mice without treatment (DM), diabetic mice with insulin treatment (subcutaneous injection of Levemir 2 units/kg body weight twice a day) (DM + Ins), diabetic mice with salicylate treatment (sodium salicylate 3 g/kg in the diets) (DM + Sal), and diabetic mice with pyridoxamine treatment (pyridoxamine dihydrochloride 1 g/L in the drinking water) (DM + Pyrid) (a). Kidney weight per body weight ratio (g/g) (b). Control (), DM (), DM + Ins (), DM + Sal (), and DM + Pyrid (). Values are mean ± SEM.

(a)

(b)