Research Article

Mechanism Investigation of the Improvement of Chang Run Tong on the Colonic Remodeling in Streptozotocin-Induced Diabetic Rats

Table 3

Fractions of AGE, RAGE, TGF-β1, and TGF-β1 receptor expressions.

ProteinsLayersConDMT1T2

AGEMucosa0.135 ± 0.027 0.196 ± 0.0280.085 ± 0.019##0.138 ± 0.029#
Muscle0.147 ± 0.040 0.474 ± 0.0650.173 ± 0.069##0.452 ± 0.099
Submucosa0.032 ± 0.011 0.167 ± 0.0350.049 ± 0.012## 0.094 ± 0.012

RAGEMucosa0.054 ± 0.007 0.113 ± 0.0400.052 ± 0.017##0.150 ± 0.041
Muscle0.189 ± 0.061 0.378 ± 0.0930.162 ± 0.042##0.423 ± 0.087
Submucosa0.059 ± 0.0330.263 ± 0.0780.071 ± 0.021##0.226 ± 0.047

TGF-β1Mucosa0.061 ± 0.0140.119 ± 0.0360.065 ± 0.012##0.194 ± 0.062
Muscle0.211 ± 0.028 0.331 ± 0.0720.191 ± 0.031#0.344 ± 0.102
Submucosa0.097 ± 0.019 0.173 ± 0.0510.099 ± 0.022##0.275 ± 0.083

TGF-β1
receptor
Mucosa0.116 ± 0.025 0.232 ± 0.0660.141 ± 0.024#0.278 ± 0.035
Muscle0.188 ± 0.008 0.422 ± 0.0790.227 ± 0.022##0.403 ± 0.044
Submucosa0.231 ± 0.0230.379 ± 0.0690.222 ± 0.017#0.399 ± 0.021

Compared with Con: , ; compared with DM: , .