Research Article
Mechanism Investigation of the Improvement of Chang Run Tong on the Colonic Remodeling in Streptozotocin-Induced Diabetic Rats
Table 3
Fractions of AGE, RAGE, TGF-β1, and TGF-β1 receptor expressions.
| Proteins | Layers | Con | DM | T1 | T2 |
| AGE | Mucosa | 0.135 ± 0.027 | 0.196 ± 0.028 | 0.085 ± 0.019## | 0.138 ± 0.029# | Muscle | 0.147 ± 0.040 | 0.474 ± 0.065 | 0.173 ± 0.069## | 0.452 ± 0.099 | Submucosa | 0.032 ± 0.011 | 0.167 ± 0.035 | 0.049 ± 0.012## | 0.094 ± 0.012 |
| RAGE | Mucosa | 0.054 ± 0.007 | 0.113 ± 0.040 | 0.052 ± 0.017## | 0.150 ± 0.041 | Muscle | 0.189 ± 0.061 | 0.378 ± 0.093 | 0.162 ± 0.042## | 0.423 ± 0.087 | Submucosa | 0.059 ± 0.033 | 0.263 ± 0.078 | 0.071 ± 0.021## | 0.226 ± 0.047 |
| TGF-β1 | Mucosa | 0.061 ± 0.014 | 0.119 ± 0.036 | 0.065 ± 0.012## | 0.194 ± 0.062 | Muscle | 0.211 ± 0.028 | 0.331 ± 0.072 | 0.191 ± 0.031# | 0.344 ± 0.102 | Submucosa | 0.097 ± 0.019 | 0.173 ± 0.051 | 0.099 ± 0.022## | 0.275 ± 0.083 |
| TGF-β1 receptor | Mucosa | 0.116 ± 0.025 | 0.232 ± 0.066 | 0.141 ± 0.024# | 0.278 ± 0.035 | Muscle | 0.188 ± 0.008 | 0.422 ± 0.079 | 0.227 ± 0.022## | 0.403 ± 0.044 | Submucosa | 0.231 ± 0.023 | 0.379 ± 0.069 | 0.222 ± 0.017# | 0.399 ± 0.021 |
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Compared with Con: , ; compared with DM: , .
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