Table 5: Relationship between serum levels of HIF-1α, VEGF, vWF, IGF-1, and 25(OH)VD3 and various factors.

VariableHIF-1αVEGFIGF-125(OH)VD3vWf
rPrPrPrPrP

Duration0.113=0.0110.123=0.0060.136=0.002−0.097=0.0310.027<0.001
FBG0.098=0.0280.024=0.5900.103=0.021−0.047=0.2980.092=0.039
HbA1c0.010=0.8240.091=0.0400.063=0.156−0.016=0.7160.081=0.069
HDL0.090=0.043−0.019=0.6720.012=0.794−0.008=0.8570.040=0.377
LDL0.111=0.0130.151=0.0010.131=0.003−0.016=0.7260.142=0.001
TC0.143=0.0010.248<0.0010.223<0.001−0.038=0.4000.190<0.001
TG0.051=0.2540.084=0.0600.105=0.019−0.084=0.0600.293<0.001
UA0.038=0.4020.201<0.0010.180<0.001−0.069=0.1230.280<0.001
Scr0.174<0.0010.253<0.0010.207<0.001−0.103=0.0200.266<0.001
BUN0.328<0.0010.367<0.0010.364<0.001−0.153=0.0010.426<0.001
eGFR−0.194<0.001−0.307<0.001−0.246<0.0010.1010.024−0.322<0.001
Fg0.278<0.0010.239<0.0010.272<0.001−0.067=0.1310.248<0.001
Ln(ACR)0.525<0.0010.715<0.0010.630<0.001−0.285<0.0010.748<0.001
FINS 0.137=0.002−0.087=0.051−0.105=0.019−0.018=0.6890.036=0.415
HOMA-IR−0.038=0.394−0.058=0.193−0.152=0.001−0.004=0.9290.072=0.109

FBG: fasting blood glucose; HbA1c: glycated hemoglobin; HDL: high-density lipoprotein; LDL: low-density lipoprotein; TC: cholesterol; TG: triglyceride; UA: uric acid; Scr: serum creatinine; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; Fg: fibrinogen; Ln(ACR): Ln Koc of urinary albumin to creatinine ratio; FINS: fasting insulin; HOMA-IR: HOMA insulin resistance index; HIF-1α: hypoxia-inducible factor-1α; VEGF: vascular endothelial growth factor; IGF-1: insulin-like growth factor-1; 25(OH)VD3: 25-hydroxy vitamin D3; vWf: von Willebrand factor.