Journal of Diabetes Research / 2016 / Article / Tab 2 / Research Article
Subclinical Alterations of Cardiac Mechanics Present Early in the Course of Pediatric Type 1 Diabetes Mellitus: A Prospective Blinded Speckle Tracking Stress Echocardiography Study Table 2 Conventional echocardiographic parameters derived from two-dimensional and Doppler imaging.
Diabetes ( ) Control ( ) valueAortic root (AoR) diameter (cm) 2.33 ± 0.35 2.41 ± 0.35 n.s. Left atrial (LA) diameter (cm) 2.56 ± 0.38 2.71 ± 0.45 n.s. LA/AoR 1.11 ± 0.16 1.13 ± 0.16 n.s. Fractional shortening (%) 33.41 ± 4.08 34.78 ± 3.94 n.s. Interventricular septal end-systolic diameter (cm) 1.06 ± 0.22 1.17 ± 0.20 0.011 Interventricular septal end-diastolic diameter (cm) 0.84 ± 0.18 0.89 ± 0.16 n.s. LV end-systolic diameter (cm) 2.70 ± 0.43 2.76 ± 0.41 n.s. LV end-diastolic diameter (cm) 4.05 ± 0.56 4.27 ± 0.46 n.s. LV posterior wall diameter, systolic (cm) 1.23 ± 0.20 1.27 ± 0.21 n.s. LV posterior wall diameter, diastolic (cm) 0.79 ± 0.16 0.81 ± 0.15 n.s. LV mass (g) 102.74 ± 41.82 115.18 ± 37.56 n.s. Relative wall thickness 0.20 ± 0.04 0.19 ± 0.03 n.s. End-diastolic volume of the left ventricle (mL) 70.18 ± 24.66 79.63 ± 27.97 n.s. End-systolic volume of the left ventricle (mL) 27.69 ± 9.82 31.66 ± 11.78 n.s. Ejection fraction (%) 61.29 ± 4.77 60.16 ± 4.67 n.s. Stroke volume (mL) 44.7 ± 14.4 49.3 ± 18.1 n.s. Cardiac output (L/min) 3.7 ± 1.1 3.7 ± 1.3 n.s. Mitral inflow: E-wave (cm/s) 95.36 ± 13.45 96.86 ± 14.26 n.s. Mitral inflow: A-wave (cm/s) 60.84 ± 12.27 57.36 ± 10.41 n.s. E-wave/A-wave 1.60 ± 0.28 1.72 ± 0.26 0.031 Mitral deceleration time (s) 0.17 ± 0.04 0.18 ± 0.04 n.s. Isovolumetric relaxation time (s) 0.05 ± 0.01 0.05 ± 0.01 n.s. S′ (cm/s) 7.92 ± 0.97 8.17 ± 1.19 n.s. E′ (cm/s) 12.54 ± 1.81 13.03 ± 1.87 n.s. A′ (cm/s) 5.42 ± 1.20 5.51 ± 1.11 n.s. E′/A′ (cm/s) 2.44 ± 0.75 2.48 ± 0.72 n.s. E/E′ (cm/s) 7.71 ± 1.20 7.56 ± 1.42 n.s.
values calculated with the Man-Whitney test, level of significance = 0.05.