Subclinical Alterations of Cardiac Mechanics Present Early in the Course of Pediatric Type 1 Diabetes Mellitus: A Prospective Blinded Speckle Tracking Stress Echocardiography Study
Table 3
Speckle tracking derived peak systolic LV strain rate at rest and during stress testing.
Diabetes ()
Control ()
value
Rest
Global circumferential strain rate (s−1)
−1.99 ± 0.28
−1.87 ± 0.24
n.s.
Circumferential strain rate (SAXM) (s−1)
−2.05 ± 0.35
−1.86 ± 0.25
0.016
Circumferential strain rate (SAXB) (s−1)
−1.96 ± 0.29
1.90 ± 0.31
n.s.
Global longitudinal strain rate (s−1)
−1.70 ± 0.44
−1.55 ± 0.21
n.s.
Longitudinal strain rate (AP4) (s−1)
−1.58 ± 0.34
−1.52 ± 0.28
n.s.
Longitudinal strain rate (AP2) (s−1)
−1.94 ± 1.14
−1.54 ± 0.25
0.019
Longitudinal strain rate (AP3) (s−1)
−1.64 ± 0.35
−1.63 ± 0.30
n.s.
Stress
Global circumferential strain rate (s−1)
−2.92 ± 0.54
−2.76 ± 0.60
n.s.
Circumferential strain rate (SAXM) (s−1)
−2.92 ± 0.58
−2.73 ± 0.61
n.s.
Circumferential strain rate (SAXB) (s−1)
−2.86 ± 0.52
−2.66 ± 0.68
n.s.
Global longitudinal strain rate (s−1)
−2.59 ± 0.47
−2.32 ± 0.41
0.021
Longitudinal strain rate (AP4) (s−1)
−2.64 ± 0.53
−2.23 ± 0.37
0.002
Longitudinal strain rate (AP2) (s−1)
−2.40 ± 0.47
−2.47 ± 0.45
n.s.
Longitudinal strain rate (AP3) (s−1)
−2.71 ± 0.72
−2.60 ± 0.75
n.s.
SAXM: parasternal short axis view at the papillary muscle plane, SAXB: parasternal short axis view at the mitral valve plane, AP4: apical four-chamber view, AP2: apical two-chamber view, and AP3: apical three-chamber view; values calculated with Man-Whitney test, level of significance = 0.05.
